Read the Vagus Nerve Impairment Self-Assessment and find out
Is Your Nervous System Causing Dramatic Symptom Crashes After Minimal Activity?
Ask yourself
- Do you experience severe symptom flares 12-48 hours after physical or mental activity, like your body sends you a delayed punishment for daring to function?
- Does even minimal effort trigger a "crash" that lasts days or weeks?
- Do you feel dramatically worse after exercise rather than energized, watching gym enthusiasts bounce back while you're bedridden for a week after a gentle walk?
- Does cognitive effort (reading, concentrating) trigger the same physical exhaustion as exercise?
If you answered yes, you may be experiencing post-exertional malaise (PEM), the cruel twist that turns normal activities into kryptonite — the hallmark symptom that distinguishes persistent fatigue from normal fatigue.
Physiological Mechanisms:
- Dysregulated energy metabolism: Chronic fatigue involves impaired energy production, turning your cellular power plants into broken-down factories — with mitochondrial dysfunction preventing cellular recovery after exertion.
- Abnormal autonomic responses: Post-exertional malaise is the distinct hallmark of persistent fatigue, distinguished by unique worsening in energy generation on repeated testing that doesn't occur in healthy individuals.
- Impaired stress recovery: The nervous system cannot properly downregulate after exertion, leading to prolonged symptom amplification that can persist for days or weeks.
Scientific backing: PEM must be present at least 50% of the time during a 6-month period for formal persistent fatigue diagnosis according to the latest IOM criteria. This distinguishes persistent fatigue from other fatiguing conditions.
Is Your Nervous System Preventing Sleep from Actually Restoring Your Energy?
Ask yourself
- Do you sleep 8+ hours but wake up feeling like you haven't slept at all, like someone switched your bed with a medieval torture device overnight?
- Do you experience frequent sleep disruptions despite feeling exhausted?
- Does sleep provide zero relief from your fatigue symptoms, making you question if you're actually sleeping or just lying there with your eyes closed for 8 hours?
- Do you wake up feeling more tired than when you went to bed?
Physiological Mechanisms:
- Severely compromised parasympathetic function: persistent fatigue patients show significantly lower heart rate variability and diminished vagal activity compared to healthy volunteers, turning sleep into a broken repair shop that never actually fixes anything — preventing restorative sleep phases.
- Disrupted sleep architecture: Reduced parasympathetic nervous system activity during sleep prevents the deep restoration necessary for energy recovery.
- Chronic autonomic hypervigilance: The nervous system maintains heightened alertness even during sleep, like a smoke detector with a dying battery that keeps beeping all night — keeping the body in a state of stress rather than repair.
Scientific backing: Unrefreshing sleep is a core diagnostic criterion for persistent fatigue, alongside cognitive impairment or orthostatic intolerance. Numerous studies find reduced parasympathetic nervous system activity during sleep in persistent fatigue patients.
Is Your Nervous System Creating Debilitating Brain Fog and Memory Problems?
Ask yourself
- Do you struggle with severe memory problems, concentration issues, and word-finding difficulties, standing in conversations grasping for words that used to come naturally?
- Does mental effort trigger immediate physical symptoms and exhaustion?
- Do you feel like your brain is "wrapped in cotton" or operating at 25% capacity, watching your former sharp mind move like dial-up internet in a high-speed world?
- Have you lost the ability to multitask or handle complex cognitive tasks?
Physiological Mechanisms:
- Neuroinflammation: Chronic neuroinflammation affects cognitive processing centers, turning your brain into a swollen, irritated organ that can barely function — with persistent fatigue patients showing activated microglia in brain imaging studies.
- Reduced cerebral blood flow: Impaired cerebral perfusion contributes to cognitive dysfunction and the sensation of mental "fog" that pervades daily activities.
- Disrupted neurotransmitter pathways: Ion channelopathies and impaired energy production at the cellular level directly affect brain function and cognitive performance.
Scientific backing: Lower HRV levels correlate directly with cognitive performance speed in persistent fatigue patients. Vagus nerve stimulation improves cognitive performance by modulating brain inflammation.
Is Your Nervous System Causing Dangerous Blood Flow Regulation Issues?
Ask yourself
- Do you feel dizzy, lightheaded, or faint when standing up from sitting or lying down, like someone drained all the blood from your head the moment you try to be vertical?
- Does your heart rate increase by 30+ beats per minute upon standing?
- Do you experience nausea, weakness, or near-fainting when upright for extended periods, making grocery shopping feel like an extreme sport?
- Do you need to sit or lie down frequently throughout the day?
Physiological Mechanisms:
- Severe autonomic dysfunction: Impaired baroreceptor and vagal regulation leads to postural heart rate abnormalities and orthostatic intolerance symptoms.
- Dysregulated blood flow: Reduced parasympathetic tone impairs vascular constriction, turning your circulatory system into a broken elevator that can't pump blood upward — leading to blood pooling in the legs and inadequate blood flow to the brain when standing.
- Cardiovascular deconditioning: Chronic illness leads to reduced blood volume and poor circulatory adaptation to position changes, exacerbating symptoms.
Scientific backing: Orthostatic intolerance is a core diagnostic feature of persistent fatigue, often involving postural heart rate abnormalities -like symptoms that can be measured through tilt table testing.”
Is Your Nervous System Contributing to Chronic Flu-Like Inflammation?
Ask yourself
- Do you experience frequent sore throats, swollen lymph nodes, or persistent flu-like symptoms, feeling like you're constantly fighting off a virus that never quite leaves?
- Do you have widespread muscle and joint pain without any injury or arthritis?
- Do you seem to catch every infection and take longer to recover than others, watching your coworkers bounce back from a cold in days while you're sick for weeks?
- Do you experience temperature regulation problems and frequent low-grade fevers?
Physiological Mechanisms:
- Chronic immune activation: Persistent activation of the innate immune system creates ongoing inflammatory responses that mimic chronic infection.
- Impaired vagal anti-inflammatory regulation: The vagus nerve's role in regulating immunity and inflammatory response is compromised, turning your immune system into a broken thermostat that can't turn off the heat — allowing inflammation to persist unchecked.
- Dysregulated cytokine production: Various cytokines act on a "fatigue nucleus" in the brain to diminish energy-consuming activities as a protective mechanism.
Scientific backing: Persistent fatigue diagnostic criteria require substantial problems with sore throat, tender lymph glands, headache, myalgia, and arthralgia. The condition involves chronic low-grade neuroinflammation.
Could a Past Infection Have Permanently Altered Your Nervous System Function?
Ask yourself
- Did your chronic tiredness symptoms begin suddenly after a viral or bacterial infection, like someone flipped a switch and your body never turned back on?
- Have you never fully recovered from illnesses like EBV, COVID-19, flu, or other infections?
- Did your health and energy levels change dramatically following a specific infection, remembering the exact moment your life divided into "before" and "after" being sick?
- Do you fit the pattern of post-infectious fatigue syndrome?
Physiological Mechanisms:
- Vagus nerve infection hypothesis: VanElzakker theorized that infections cause the vagus nerve to mistakenly enhance fatigue signals to the central nervous system, turning your body's communication system into a broken phone line that only transmits exhaustion — creating persistent symptoms.
- Glial cell activation: Infections near glial cells surrounding the vagus nerve trigger proinflammatory cytokine release, leading to pathologically exaggerated fatigue responses.
- Molecular mimicry: Autoimmunity due to molecular mimicry between pathogen and host proteins can trigger ongoing symptoms that persist long after the initial infection clears.
Scientific backing: 27% of SARS survivors developed chronic tiredness four years post-infection. Nearly half of Post-Viral patients fulfill 1994 criteria for chronic tiredness. Mount Sinai study showed 57% of Post-Viral chronic tiredness patients improved with vagus nerve stimulation.
Exploring Nurosym Vagus Nerve activation as a better path to Chronic Tiredness Syndrome management
Nurosym neuromodulation offers an immediate, effortless way to regulate your nervous system and start gaining control over chronic tiredness syndrome symptoms.
Instant effect in minutes
Just wear it and let it work. No need to practice techniques or change your routine.
50+ scientific studies
Scientifically proven in collaboration with leading institutions like Harvard, UCLA, NHS
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0 serious adverse events in studies to date. No dependency.
Trusted by leading wellness professionals and scientists
User stories and results
Chronic Tiredness Syndrome Managing Stress & Sleep with Nurosym: A Chronic Tiredness Success Story
“I’ve been using it for my chronic tiredness syndrome… I’ve noticed better overall management of my mood, stress, and sleep since starting this device. It’s been probably within the first 30 days where I noticed the benefits of this. And I definitely feel like I will continue to use it as part of my daily routine.”
ME/Chronic Tiredness Verified Trustpilot Review
“I have had Chronic Tiredness since Autumn 23… Exhaustion, nausea, headaches, brain fog, mental and cognitive impairment… I bought the Nurosym on January 25 and it’s certainly helped me. It has had a significant impact on reducing my headaches, improved the quality of my sleep, eased anxiety and my mental and cognitive abilities have improved a lot.”
Chronic Tiredness Syndrome with Sleep Issues Verified Trustpilot Review
“I got Nurosym to help me with my Chronic Tiredness Syndrome and have to say that I got what I expected. Been using it for 10 months and the Nurosym device is working great – I feel slight improvement with my sleep and anxiety levels. Doesn’t ‘cure’ the Chronic Tiredness Syndrome but at least I can feel some improvement which is great.”
Post-Viral Chronic Tiredness Verified Trustpilot Review
“I have got chronic tiredness, Post-Viral Fatigue, and because of that, I got persistent depressive states/low mood. In addition, I am very impulsive and often stressed. For many months, I have been using the Nurosym wearable device on a daily basis. I felt a significant improvement in many of my health symptoms.”
Chronic Tiredness & Brain Fog Featured Testimonial
“I’ve had a very good experience with it, and I’d recommend it to anybody who was hoping for relief, particularly from chronic tiredness and brain fog symptoms.”
Meet The Doctors
A practicing doctor of psychiatry, Elisabetta has an MBA from INSEAD Business School, and experience in direct patient care, neuroscience research, communication and management. Dr. Burchi is a physician-scientist, working with Parasym in scientific affairs with a track record of publishing in the most important scientific journals such as The Lancet, writing successful grant proposals for the NIH, and leading the production of editorial, scientific, regulatory and promotional material in collaborative multidisciplinary teams. Dr. Burchi has also coordinated scientific studies and implemented a tele-medicine practice which received a certification of excellence among more than 100,000 professionals.
Dr. Elisabetta Burchi, MD, MBA
Translational research lead at Parasym
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Claim €70 OFF the most studied vagal neuromodulation device in the world.
Take part in our study to advance research in neuromodulation and claim €70 subsidy on your device.
*Takes less than 2 minutes to complete.
50+
Ongoing scientific studies
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Happy user sessions
30
Day money back guarantee
Certified medical device
30 Day Money-back Guarantee
If you try Nurosym daily for 30 days and aren’t happy with your results, we’ll send you a full refund of your Nurosym Kit. No questions asked Given the remarkable results Nurosym has had in scientific studies and with our customers around the world, we’re confident in its health-restoring effects.
Our goal will always be to restore our collective health – restoring health for as many people as we can and in turn, restoring the health of our planet. If Nurosym doesn’t work for you for any reason, we’re happy to send you a refund. This refund period is available 30 days after the date of purchase and expires the following week (37 days after the date of purchase). The refund will be issued once we receive your tracking code for the return.
To receive a refund: contact us
Got questions? Here is everything you need to know
Symptoms we studied
These symptoms have been linked to autonomic nervous system imbalance and Vagus Nerve Impairment in Chronic Tiredness Syndrome patients:
- Chronic tiredness and Post-Exertional Malaise (PEM)
- Unrefreshing sleep and sleep disorders
- Cognitive impairment and brain fog
- Orthostatic intolerance and Postural heart rate abnormalities symptoms
- Widespread pain and muscle aches
- Immune dysfunction and frequent infections
- Temperature regulation problems
- Digestive issues and gut motility problems
- Post-viral symptoms and autoimmune-like reactions
Our latest research data also suggests Nurosym improves learning and short-term memory and cognition.
Nurosym also has been shown to promote relaxation, mood, sleep, healthy digestion, increased HRV, as well as to alleviate symptoms of stress, burnout, adrenal fatigue.
When can I start feeling the effects?
The timeframe for experiencing the effects of Nurosym varies. Individuals with severe symptoms may notice improvements within 1 to 3 days, while others may see results within 4 to 6 weeks. Rest assured, the transformative benefits of Nurosym will be within reach.
Is Nurosym safe for Chronic Tiredness Syndrome patients?
Neuromodulation via Nurosym is considered safe when used as intended.
Nurosym has these certificates.
– It is based on scientific evidence
– It is safe to use
– It has demonstrated scientific efficacy
Be sure to read the important safety information before use. Thousands of users have tested the device and no serious adverse effects have been reported in studies to date.
What does it feel like?
Feels like a pleasant, light vibration or tingling sensation in your ear.
Are there any additional costs or subscription fees?
There are no additional costs or fees, only the one-time purchase of the Nurosym.
How long should I use Nurosym each day for optimal results?
We recommend using Nurosym for 1 hour each day, however, benefits can be seen with as little as 15 minutes of use.
Can I perform other activities while using it?
Yes, you can experience the benefits of Neurostimulation anywhere, anytime while doing any activity.
Do I need a prescription to purchase Nurosym?
No. However, we recommend that you consult with your health professional if you’re unsure whether Nurosym is right for you.
What are the details of your 30-day guarantee?
If you try Nurosym daily for 30 days and aren’t happy with your results, we’ll send you a full refund. No questions asked.
Does Nurosym come with a warranty?
Yes! We offer a one-year warranty with every Nurosym device.
How long do orders take to ship?
Orders are processed and dispatched within 1-3 business days.
What is in the Nurosym Package?
- Nurosym device
- Earpiece
- USB charger
- Case
- Quick start guide
The article does not in any way constitute as medical advice. Please seek consultation with a licensed medical professional before starting any treatment. This website may receive commissions from the links or products mentioned in this article.
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That delayed crash after activity? Exactly my life right now.