Read the Vagus Nerve Impairment Self-Assessment and find out
Is Your Nervous System Keeping You in Persistent Post-Viral Fatigue and Brain Fog?
Ask yourself
- Do you experience overwhelming tiredness that doesn't improve with rest, even months after your initial COVID infection?
- Does your brain feel foggy, with difficulty concentrating, remembering things, or finding words?
- Do you feel mentally and physically exhausted after minimal exertion that you could easily handle before COVID?
If you answered yes, your nervous system may be stuck in a dysregulated state following your viral infection, preventing proper recovery and cognitive function.
Physiological Mechanisms:
- Post-viral autonomic dysfunction: COVID-19 can damage the vagus nerve and disrupt autonomic function, leading to persistent tiredness and cognitive impairment that resembles chronic tiredness syndrome.
- Neuroinflammation persistence: Ongoing inflammation in the brain disrupts neurotransmitter balance, affecting dopamine, serotonin, and acetylcholine pathways critical for energy and cognition.
- Mitochondrial dysfunction: Viral infection can impair cellular energy production, leading to profound tiredness and reduced mental clarity that persists long after initial recovery.
Post-viral neurological symptoms may be directly linked to autonomic nervous system dysfunction, with the vagus nerve playing a critical role in post-viral recovery and cognitive restoration.
Is Your Nervous System Contributing to Post-Viral Heart Palpitations and Exercise Intolerance?
Ask yourself
- Do you experience rapid heart rate, palpitations, or chest tightness that started after COVID?
- Does minimal physical activity leave you feeling breathless or cause your heart to race excessively?
- Do you struggle with exercise intolerance, unable to reach previous fitness levels without severe symptoms?
Physiological Mechanisms:
- Post-viral Postural Heart Rate Abnormalities: COVID-19 can trigger postural orthostatic rapid heartbeat syndrome, causing abnormal heart rate responses and exercise intolerance through autonomic dysregulation.
- Vagal nerve impairment: Viral damage to the vagus nerve reduces its ability to regulate heart rate variability and maintain cardiovascular stability during activity.
- Dysregulated stress response: Persistent sympathetic nervous system activation leads to heightened cardiovascular reactivity and reduced exercise tolerance.
Post-viral cardiovascular symptoms often reflect autonomic nervous system dysfunction rather than direct heart damage, explaining why standard cardiac tests may appear normal despite persistent symptoms.
Is Your Nervous System Contributing to Post-Viral Shortness of Breath and Air Hunger?
Ask yourself
- Do you frequently experience shortness of breath or feel like you can't take a deep, satisfying breath?
- Does talking, walking, or mild exertion leave you breathless in ways that didn't happen before COVID?
- Do you experience "air hunger" - a feeling that you're not getting enough oxygen despite normal oxygen levels?
Physiological Mechanisms:
- Vagal respiratory control disruption: COVID-19 can impair vagus nerve regulation of the diaphragm and breathing patterns, leading to dysfunctional breathing even after lung recovery.
- Autonomic breathing dysregulation: Disrupted autonomic control can cause irregular breathing patterns, hyperventilation, or inability to take deep breaths.
- Central nervous system effects: Viral impact on brainstem respiratory centers can persist, causing ongoing breathing difficulties despite clear lungs.
Post-viral breathing difficulties may originate from nervous system dysregulation rather than lung damage, which is why pulmonary function tests often appear normal despite persistent symptoms.
Is Your Nervous System Causing Post-Viral Digestive Issues?
Ask yourself
- Do you experience new or worsened digestive issues like nausea, bloating, or changes in bowel habits since COVID?
- Have you developed food intolerances or sensitivities that weren't present before your infection?
- Do you struggle with loss of appetite, early satiety, or delayed gastric emptying-like symptoms?
Physiological Mechanisms:
- Gut-brain axis disruption: COVID-19 can damage the enteric nervous system and vagal pathways that control digestion, leading to delayed gastric emptying and motility disorders.
- Dysbiosis and inflammation: Viral infection can alter gut microbiome balance and increase intestinal permeability, contributing to ongoing digestive dysfunction.
- Vagal gastroparesis: Impaired vagus nerve function can slow gastric emptying and reduce digestive enzyme production, causing persistent gastrointestinal symptoms.
Post-viral gastrointestinal symptoms often reflect vagus nerve dysfunction and gut-brain axis disruption, requiring approaches that address nervous system regulation rather than just digestive symptoms.
Is Your Nervous System Contributing to Post-Viral Sleep Disruption and Non-Restorative Rest?
Ask yourself
- Do you struggle with frequent night wakings, or difficulty falling asleep since having COVID?
- Do you wake up feeling unrefreshed and exhausted, no matter how many hours you sleep?
- Has your sleep architecture changed, with less deep sleep or vivid, disturbing dreams?
Physiological Mechanisms:
- Circadian rhythm disruption: COVID-19 can affect the hypothalamic-pituitary axis and disrupt natural sleep-wake cycles, leading to persistent sleep problems and non-restorative sleep.
- Autonomic sleep regulation impairment: Damaged vagus nerve function prevents proper transition into parasympathetic dominance needed for deep, restorative sleep.
- Persistent hypervigilance: Ongoing sympathetic nervous system activation keeps the body in an alert state, preventing the relaxation necessary for quality sleep.
Post-viral sleep disorders often stem from autonomic nervous system dysregulation, where the body cannot shift into the parasympathetic state necessary for restorative sleep, regardless of tiredness levels.
Are Your Post-Viral Symptoms Part of a Post-Viral Autonomic Syndrome?
Ask yourself
- Do you experience multiple unexplained symptoms that seem unrelated but all started after COVID?
- Have you developed new sensitivities to temperature, light, sound, or stress that weren't present before?
- Do your symptoms fluctuate unpredictably, with good and bad days that don't correlate with your activity level?
Physiological Mechanisms:
- Multi-system autonomic dysfunction: COVID-19 can trigger widespread autonomic nervous system dysfunction affecting multiple organ systems simultaneously, creating the complex symptom pattern of persistent post-viral symptoms.
- Autoimmune autonomic neuropathy: Post-viral autoimmune responses can target autonomic nerve fibers, leading to persistent dysfunction across multiple body systems.
- Central sensitization: Viral-induced neuroinflammation can increase nervous system sensitivity, causing symptoms to persist and fluctuate unpredictably long after initial infection.
Post-infectious complications represent a post-viral autonomic syndrome where SARS-CoV-2 triggers lasting dysfunction in the nervous system’s control of vital functions, explaining the diverse and persistent nature of symptoms.
The Missing Piece in Extended SARS-Cov-2 Understanding
Here’s what connects all these post-viral symptoms: your vagus nerve orchestrates every one of these recovery processes.
The vagus nerve serves as your body’s primary recovery pathway, regulating inflammation, coordinating organ function, and facilitating the return to homeostasis after viral insult. When COVID-19 disrupts this system, the cascade of persistent symptoms becomes not just explainable, but addressable.
Research shows vagus nerve stimulation can modulate inflammatory responses and improve autonomic balance, offering new insights into post-viral recovery mechanisms.
Advancing SARS-Cov-2 Research Through Vagus Nerve Modulation
Recent scientific research has begun exploring transcutaneous vagus nerve stimulation as a potential intervention for post-viral autonomic dysfunction. Nurosym represents the most studied approach in this emerging field.
Research Highlights:
Scientific Validation
Over 50 peer-reviewed studies examining vagus nerve stimulation across multiple symptoms, with specific research ongoing for post-viral symptoms.
Institutional Collaboration
Studies conducted in partnership with Harvard, UCLA, NHS, and other leading research institutions.
Safety Profile
Zero serious adverse events reported across scientific studies to date, with regulatory approval as a medical device.
Perspectives from the Medical Community
Understanding the Science
Current research suggests that vagus nerve stimulation may help address lingering COVID effects through several mechanisms:
- Inflammatory modulation: Activation of the cholinergic anti-inflammatory pathway
- Autonomic rebalancing: Restoration of sympathetic-parasympathetic equilibrium
- Neuroplasticity enhancement: Support for neural recovery and adaptation
- Sleep architecture improvement: Facilitation of restorative sleep cycles
- HRV optimization: Enhancement of heart rate variability markers
These physiological changes align with the core dysfunctions observed in prolonged symptoms, suggesting a mechanistic basis for therapeutic intervention.
Ongoing SARS-Cov-2 Research
The scientific community continues to investigate vagus nerve stimulation for post-viral recovery.
Current Studies:
- Post-viral fatigue and cognitive function
- Autonomic dysfunction in SARS-Cov-2
- Sleep disorders following viral infection
- Exercise intolerance and cardiovascular symptoms
- Gastrointestinal recovery post-COVID
Research Participation: Individuals with post-viral symptoms may be eligible to participate in ongoing research studies while accessing potential therapeutic interventions.
Symptoms Under Investigation
Research is examining vagus nerve stimulation’s potential impact on these post-viral manifestations:
- Post-viral fatigue and energy regulation
- Cognitive dysfunction and brain fog
- Cardiovascular symptoms and exercise intolerance
- Respiratory difficulties and breathing patterns
- Sleep architecture and restorative rest
- Gastrointestinal function and digestion
- Temperature regulation and autonomic control
- Neurological symptoms and sensory processing
- Mood regulation and stress response
- Pain modulation and inflammatory markers
The interconnected nature of these symptoms supports the hypothesis that addressing autonomic dysfunction may provide systemic benefits for post-viral recovery.
A Note on Therapeutic Approaches
While ongoing SARS-Cov-2 research continues to evolve, early evidence suggests that approaches targeting nervous system regulation may offer advantages over symptom-specific therapies.
The autonomic nervous system’s role as a master regulator of physiological function makes it a logical therapeutic target for multi-system post-viral dysfunction.
Current management strategies often address individual symptoms in isolation.
However, understanding SARS-CoV-2 infection as a unified autonomic syndrome suggests that interventions supporting overall nervous system recovery may provide more comprehensive benefits.
Individual results may vary. This information is for educational purposes and should not replace consultation with healthcare professionals familiar with your specific medical situation.
Research Disclaimer: This content discusses ongoing research and should not be considered medical advice. Extended COVID management should involve qualified healthcare providers. Research participation and device use should be discussed with your medical team.
Cómo elegir un estimulador del nervio vago
Con la gran variedad de dispositivos disponibles en el mercado, es importante investigar bien y elegir el que mejor se adapte a tus necesidades. Lo más importante es asegurarte de que la intervención que estás considerando haya sido científicamente probada para actuar sobre el nervio vago.
Estos son algunos de los factores clave que hay que tener en cuenta a la hora de tomar una decisión:
- Consult with your health care professional
Antes de comenzar cualquier nueva intervención médica, siempre es recomendable consultar primero con un profesional sanitario. Para la estimulación del nervio vago, elija un neurólogo o especialista que esté familiarizado con los dispositivos de VNS, para que pueda aconsejarle correctamente sobre si le ayudará con sus síntomas específicos. - Compatibilidad con tus síntomas
Los dispositivos VNS están diseñados para mejorar síntomas específicos, como estados depresivos, cansancio crónico, problemas gastrointestinales y confusión mental. Asegúrate de que la estimulación del nervio vago haya sido estudiada y evaluada en cuanto a su eficacia para tus necesidades de salud específicas. Los dispositivos VNS también tienen diferentes ubicaciones de estimulación, como el cuello y la oreja. Sensate, que no es un dispositivo VNS, afirma estimularlo a través del pecho. Sin embargo, Nurosym’s AVNT approach and Gammacore’s approach both have scientific evidence of precise targeting and safety. Other approaches at any location are at best playing the piano out of tune and at worst actively dangerous. - Seguridad y certificación como dispositivo portátil
Muchos dispositivos afirman ser dispositivos VNS y ser seguros, pero es importante evaluar la investigación científica realizada sobre cada dispositivo para comprender su perfil de seguridad. Sensate y Pulsetto afirman que activan el nervio vago, pero no tienen ninguna evidencia científica que lo confirme. Los diferentes métodos de estimulación del nervio vago también están asociados a diferentes efectos secundarios, por lo que es conveniente comprender todos los riesgos antes de comprar. Los dispositivos que han obtenido la certificación Wearable Device son fundamentales, ya que esta certificación requiere rigurosas pruebas de calidad y estudios de seguridad para garantizar que no dañan el sistema nervioso. - Eficacia e investigación
Asegúrese de buscar dispositivos respaldados por investigaciones científicas y, a ser posible, estudios controlados con placebo. Un dispositivo de buena reputación habrá publicado investigaciones que respalden sus afirmaciones. Las pruebas aleatorias controladas con placebo garantizan que los efectos de un dispositivo no se basan en el placebo, lo que da confianza en los beneficios terapéuticos reales del dispositivo. Del mismo modo, los estudios revisados por pares reducen el riesgo de resultados sesgados y demuestran la credibilidad del dispositivo probado.Muchos dispositivos citan investigaciones genéricas sobre la VNS, pero no han realizado ningún estudio de seguridad y eficacia sobre su dispositivo. El hecho de que un dispositivo emita una corriente eléctrica en la zona donde se encuentra el nervio vago no garantiza que active el nervio vago ni que tenga un impacto positivo en él. La mayoría de las investigaciones sobre la estimulación del nervio vago se realizaron con métodos invasivos, no con dispositivos portátiles. Por lo tanto, un dispositivo portátil que hace referencia a investigaciones invasivas sobre la VNS está tergiversando los datos para vender su producto.
- Estimulación frente a modulación
También es importante tener en cuenta que algunos dispositivos, como Pulsetto o GammaCore, proporcionan una estimulación de alta intensidad que puede aumentar la probabilidad de efectos secundarios y puede perjudicar a las personas con síntomas crónicos cuyo sistema nervioso ya está desregulado. Nurosym con 45 niveles de energía ofrece un control preciso de la modulación para proporcionar los mismos beneficios con menos riesgos.
- Precio
El dispositivo que elijas debe ajustarse a tu presupuesto. Algunos dispositivos tienen un modelo de suscripción que requiere pagos continuos a lo largo del tiempo. Otros, como Nurosym y Sensate son compras únicas. Dado que los beneficios del uso de la VNS requieren un uso constante, cuanto más se utilicen, mejores serán los resultados. Por lo tanto, al considerar la adquisición de un dispositivo, piense a largo plazo en cómo se acumularían los costes de su uso prolongado. Tomando Nurosym por ejemplo, el coste medio del dispositivo es de aproximadamente 2 euros al día durante un año, y después ya no hay que realizar más pagos. Por su parte, GammaCore viene precargado con sesiones para tres meses. Después, será necesario adquirir más sesiones para seguir utilizándolo. Pulsetto ofrece una suscripción de pago a la aplicación, por lo que los costes de uso a largo plazo pueden acumularse.
Protocolo de pruebas
Since these devices are NOT created equal, it’s essential to carefully evaluate their features, effectiveness, and user experience before making a decision. So we set out to compare four of the most popular devices that people purchase for vagus nerve stimulation – Pulsetto, Sensate, Gammacore, and Nurosym. Sin embargo, es importante señalar que, a diferencia de Nurosym y GammaCore, Pulsetto y Sensate no son dispositivos VNS certificados.
Para realizar una comparación precisa, cada dispositivo fue evaluado por un equipo de doctores y profesionales sanitarios. Utilicé cada dispositivo durante un mes, con un descanso de un mes entre cada uno para evitar cualquier efecto residual. Empecé con Sensate, luego Pulsetto, Nurosym, y por último, GammaCore.
Aquí están los resultados y las clasificaciones:
| Nurosym | Gammacore | Pulsetto | Sensate | |
| Evaluado y respaldado por estudios científicos revisados por pares y controlados con placebo | ✓ | ✓ | Χ | Χ |
| Número de estudios científicos realizados | 40+ | 20+ | 0 | 0 |
| Scientific studies investment | $10M+ | $50M+ | $0 | $0 |
| Se puede usar sin aplicación | ✓ | Χ | Χ | Χ |
| Disponible sin receta médica | ✓ | Χ | ✓ | ✓ |
| Modo de acción | Terapia de neuromodulación vagal auricular (AVNT) | Estimulación no invasiva del nervio vago cervical (ncVNS) | Sin modo de acción validado. | Sin modo de acción validado. |
| Zona de aplicación | Rama auricular del nervio vago | Cervical branch of the vagus nerve | Neck | Pecho |
| Entrega | Propio (Eléctrico) | Propio (Eléctrico) | Eléctrico | Vibración |
| Agradabilidad de la estimulación | Agradable, suave | Más intenso, puede apretar la mandíbula. | Más intenso | Sin estimulación directa, vibración agradable. |
| ¿Es necesario usar gel? | No | Yes | Yes | No |
| Duración de la batería | >1 mes | 1 semana | 1 semana | 1 semana |
| Fácil de llevar de viaje | Yes | No | No | Yes |
| Tipo de dispositivo que requiere revisión y aprobación reglamentaria antes de su comercialización | Obligatorio | Obligatorio | Obligatorio | Χ |
| Aprobado para uso público | ✓ | ✓ | Χ | n/a |
| Dispositivo portátil certificado | ✓ | ✓ | Χ | Χ |
| Proceso de evaluación médica en la compra | ✓ | ✓ | Χ | Χ |
| Controles de seguridad documentados | ✓ | ✓ | Χ | Χ |
| SAE (eventos adversos graves) notificados en un estudio científico | 0 | 0 | No hay evaluación científica. Se han notificado efectos adversos en Internet. | Sin evaluación científica. |
| Perfil de riesgo | Bajo riesgo según estudios científicos | Bajo riesgo según estudios científicos | Alto riesgo debido a la falta de estudios científicos e informes de usuarios | Bajo riesgo basado en la entrega (vibración) |
| Coste inicial | £599 | 350 £ (solo los primeros 3 meses) | £209.20 | £299 |
| Costes adicionales | £0 | 466 £ cada 3 meses | 99,99 £ al año. Aplicación de pago con más funciones | 50 £ al año. Aplicación de pago con más funciones |
| Coste total estimado durante 5 años de uso diario | £599 | £10,718 | £709.15 | £549 |
| Recomendación general | Our top pick – Highly recommended | Recomendado para personas que sufren de dolor de cabeza | No recomendado |
Se puede utilizar como herramienta complementaria |
Meet The Doctors
A practicing doctor of psychiatry, Elisabetta has an MBA from INSEAD Business School, and experience in direct patient care, neuroscience research, communication and management. Dr. Burchi is a physician-scientist, working with Parasym in clinical affairs with a track record of publishing in the most important scientific journals such as The Lancet, writing successful grant proposals for the NIH, and leading the production of editorial, clinical, regulatory and promotional material in collaborative multidisciplinary teams. Dr. Burchi has also coordinated clinical trials and implemented a tele-medicine practice which received a certification of excellence among more than 100,000 professionals.
Dr. Elisabetta Burchi, MD, MBA
Translational research lead at Parasym
Experience The Future of Bioelectronic Medicine
Claim €70 OFF the most studied vagal neuromodulation device in the world.
Take part in the study to advance research in neuromodulation and claim €70 subsidy on your device.
*Takes less than 2 minutes to complete.
50+
Ongoing scientific studies
4M+
Happy user sessions
30
Day money back guarantee
Certified medical device
Claim €70 OFF the most studied vagal neuromodulation device in the world.
Take part in the study to advance research in neuromodulation and claim €70 subsidy on your device.
*Takes less than 2 minutes to complete.
50+
Ongoing scientific studies
4M+
Happy user sessions
30
Day money back guarantee
Certified medical device
30 Day Money-back Guarantee
Every Nurosym Kit is backed by a 30-day, full-refund policy if users aren’t satisfied with their progress.
Got questions? Here is everything you need to know
Symptoms we studied
These symptoms have been linked to autonomic nervous system imbalance and Vagus Nerve Impairment:
- Chronic Tiredness, Fatigue, Brain Fog, Burnout
- Sleep problems
- Negative thought
- Inflammatory symptoms
- Pain, headaches
- Memory & Attention problems
- Post-Viral Symptoms
- Widespread body pain
Our latest research data also suggests Nurosym improves learning and short-term memory and cognition.
Nurosym also has been shown to promote relaxation, mood, sleep, healthy digestion, increased HRV, as well as to alleviate symptoms of stress, burnout, adrenal fatigue.
When can I start feeling the effects?
The timeframe for experiencing the effects of Nurosym varies. Individuals with severe symptoms may notice improvements within 1 to 3 days, while others may see results within 4 to 6 weeks. Rest assured, the transformative benefits of Nurosym will be within reach.
Nurosym está a salvo?
Neuromodulation via Nurosym is considered safe when used as intended. Nurosym has been certified by EU regulators as CE certified medical device. This means:
– It is based on scientific evidence
– It is safe to use
– It has demonstrated scientific efficacy
Be sure to read the important safety information before use. Thousands of users have tested the device and no serious adverse effects have been reported in studies to date.
What does it feel like?
Feels like a pleasant, light vibration or tingling sensation in your ear.
Are there any additional costs or subscription fees?
There are no additional costs or fees, only the one-time purchase of the Nurosym.
How long should I use Nurosym each day for optimal results?
We recommend using Nurosym for 1 hour each day, however, benefits can be seen with as little as 15 minutes of use.
Can I perform other activities while using it?
Yes, you can experience the benefits of Neurostimulation anywhere, anytime while doing any activity.
Do I need a prescription to purchase Nurosym?
No. However, we recommend that you consult with your health professional if you’re unsure whether Nurosym is right for you.
What are the details of your 30-day guarantee?
If you try Nurosym daily for 30 days and aren’t happy with your results, we’ll send you a full refund. No questions asked.
Does Nurosym come with a warranty?
Yes! We offer a one-year warranty with every Nurosym device.
How long do orders take to ship?
Orders are processed and dispatched within 1-3 business days.
What is in the Nurosym Package?
- Nurosym device
- Earpiece
- USB charger
- Case
- Quick start guide
El artículo no constituye en modo alguno un consejo médico. Consulte con un profesional médico autorizado antes de iniciar cualquier tratamiento. Este sitio web puede recibir comisiones por los enlaces o productos mencionados en este artículo.
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